There are no known issues. What kinds of problems are you having? That will definitely help us provide some possible solutions if there things we've heard of with JomSocial in general before.
Finally, please make sure you're running the latest version of JFBConnect v4.0.3 as well, which has been tested quite a bit with JS 2.4, and has been reported by other users to have no issues as well.
Thanks,
Alex