Babar,
I just created an account, but can't see the issue you describe. When I click my name on the right, the "Profile" link on the top menu, or my avatar on the home page, I'm brought to my profile page below and in each case, it works:
j1-5.pakistanrc.com/mynx_rtl/index.php?o...userid=66&Itemid=100
It looks like SEF is turned off now, so maybe that's why it's working right now. In AceSEF, you should be able to tell it to ignore JFBConnect so it doesn't try to change our URLs. However, since what you describe seems to be more of an issue when looking at a JomSocial profile, I'm not sure if this will help.
Let us know if you configure it again in a way that it fails, and if so, tell us exactly where to click, and we'll test again.
Thanks, and good luck!