JFBConnect works with any extension, really. While there are certain ones we have additional integration with (for importing profile information, for instance), you can use the Like button, comment boxes, and other social widgets on any page of your site. Additionally, the login/registration features from Facebook create a standard Joomla user that can be used with any other component.
Hope that answers your question, but if you have more specifics about exactly what you're looking for, just let us know!
Alex